| October |
| | 31 | 4:00PM | Indiana Tech | vs. | Olivet Nazarene University | 87-80 | |
| | University of St. Francis Tournament |
| November |
| | 1 | 3:00PM | UM-Dearborn | @ | Grace Bible College | 67-79 | |
| | | 6:00PM | Indiana Tech | @ | University of Saint Francis | 96-88 | (OT) |
| | University of St. Francis Tournament |
| | | 7:00PM | Marygrove College | @ | Concordia | 66-75 | |
| | | 7:30PM | Kuyper College | @ | Davenport | 39-83 | |
| | First win for Head Coach Burt Paddock |
| | 3 | 7:30PM | St. Francis | @ | Madonna | 89-66 | |
| | 4 | 7:30PM | Andrews University | @ | Davenport | 34-71 | |
| | First Ever 2-0 Start in DU History |
| | | 8:00PM | Cornerstone | @ | Kuyper College | 136-77 | |
| | 5 | 7:00PM | Huntington College | @ | Indiana Tech | 69-71 | |
| | | 7:30PM | Spring Arbor University | @ | Concordia | 77-54 | |
| | 7 | 5:00PM | Siena Heights | vs. | Brescia University | 68-73 | (OT) |
| | Goshen Tournament |
| | | 7:00PM | Cornerstone | vs. | Saint Xavier University | 82-66 | |
| | Trinity Christian Classic |
| | | 8:00PM | Davenport | vs. | Calumet College of St. Joseph | 86-64 | |
| | Bethel College (IN) Classic |
| | 8 | 1:00PM | Davenport | vs. | Purdue University-North Central | 73-52 | |
| | Bethel College (IN) Classic |
| | | 1:00PM | Siena Heights | vs. | Holy Cross College | 98-72 | |
| | Goshen Tournament |
| | | 2:30PM | UM-Dearborn | @ | Trevecca Nazarene University | 62-67 | |
| | | 4:00PM | Cornerstone | @ | Trinity Christian College | 87-74 | |
| | Trinity Christian Classic |
| | 11 | 7:30PM | Goshen College | @ | Davenport | 82-92 | |
| | | 7:30PM | UM-Dearborn | @ | Indiana Wesleyan University | 45-87 | |
| | | 8:00PM | Trinity International University | @ | Cornerstone | 74-83 | |
| | | 8:00PM | Madonna | @ | Spring Arbor University | 65-77 | |
| | Game can be heard live on MadonnaCrusaders.com |
| | 12 | 7:30PM | Holy Cross College | @ | Concordia | 64-92 | |
| | 14 | 6:00PM | Concordia | vs. | Cardinal Stritch University | 67-73 | |
| | Huntington College Tournament - Huntington, Ind. |
| | | 6:00PM | Aquinas | vs. | Indiana Wesleyan University | 49-61 | |
| | | 8:00PM | Madonna | vs. | Shawnee State University | 66-83 | |
| | Shawnee State Tournament - Shawnee, Ohio - Nov. 14-15 |
| | | 8:00PM | Spring Arbor University | @ | Cornerstone | 91-93 | |
| | WHAC/MCC Challenge |
| | | 8:00PM | Holy Cross College | @ | Siena Heights | 53-74 | |
| | Maple City Classic |
| | 15 | | Davenport | @ | Grand Valley State | 65-77 | |
| | | 1:00PM | Madonna | vs. | Cedarville University | 65-81 | |
| | Shawnee State Classic; Portsmouth, OH |
| | | 1:00PM | Concordia | vs. | Kuyper College | 83-49 | |
| | Huntington College Tournament - Huntington, Ind. |
| | | 2:00PM | Aquinas | vs. | Spring Arbor University | 56-67 | |
| | | 3:00PM | Calumet College of St. Joseph | @ | UM-Dearborn | 55-77 | |
| | | 3:00PM | Indiana Wesleyan University | @ | Cornerstone | 68-59 | |
| | WHAC/MCC Challenge |
| | | 6:00PM | Brescia University | @ | Indiana Tech | 70-88 | |
| | | 8:00PM | University of Saint Francis | @ | Siena Heights | 73-70 | |
| | Maple City Classic - Championship Game |
| | 18 | 7:00PM | Rochester College | @ | UM-Dearborn | 55-57 | |
| | | 7:00PM | Cornerstone | @ | University of Saint Francis | 78-86 | |
| | | 7:00PM | Siena Heights | @ | Spring Arbor University | 70-73 | (OT) |
| | | 7:00PM | Indiana Wesleyan University | @ | Indiana Tech | 79-84 | (OT) |
| | | 8:00PM | Olivet College | @ | Aquinas | PPD | |
| | Ppd., power failure; rescheduled for 6 p.m. 11/19/2008 |
| | 19 | 8:00PM | Olivet College | @ | Aquinas | 68-67 | |
| | Rescheduled from Nov. 18 |
| | 21 | | Indiana Tech | vs. | Illinois Institute of Technology | 105-63 | |
| | Marian University Tournament |
| | | 3:00PM | Concordia | vs. | Andrews University | 62-54 | |
| | Concordia advances to championship game |
| | | 5:30PM | Siena Heights | vs. | Point Park College | 90-74 | |
| | Daemen Tournament |
| | | 7:00PM | Aquinas | @ | Metropolitan State College of Denver | 50-65 | |
| | Metro State Tournament |
| | 22 | | Indiana Tech | @ | Marian College | 59-82 | |
| | Marian University Tournament |
| | | 3:00PM | Madonna | vs. | Defiance College | 67-78 | |
| | Albion Tournament - Albion, Mich. - Nov. 22-23 |
| | | 3:00PM | UM-Dearborn | @ | Wilberforce University | 61-57 | |
| | | 3:00PM | Grace College | @ | Cornerstone | 70-82 | |
| | | 4:00PM | Siena Heights | @ | Daemen College | 77-96 | |
| | Daemen Tournament |
| | | 5:30PM | Concordia | vs. | Notre Dame College | 71-80 | (2OT) |
| | Notre Dame Wins Olivet Classic in 2OT |
| | | 7:00PM | Aquinas | vs. | Colorado Christian | 67-72 | |
| | Metro State Classic |
| | | 8:00PM | Davenport | vs. | Eastern Mennonite University | 85-74 | |
| | Bridgewater (VA) Classic |
| | 23 | 3:00PM | Madonna | @ | Albion College | 64-77 | |
| | Albion Tournament - Albion, Mich. - Nov. 22-23 |
| | | 4:00PM | Davenport | @ | Bridgewater College | 71-61 | |
| | Bridgewater (VA) Classic |
| | 25 | 7:00PM | Indiana Tech | @ | Taylor University-Ft. Wayne | 82-57 | |
| | | 7:30PM | Concordia | @ | Alma College | 75-63 | |
| | | 7:30PM | Madonna | @ | Rochester College | 49-78 | |
| | Game played at Rochester HS |
| | 28 | 6:00PM | Aquinas | vs. | Calvin College | 78-73 | |
| | GR Sports Hall of Fame Classic |
| | | 8:00PM | Cornerstone | @ | Hope College | 74-82 | |
| | Hall of Fame Tournament |
| | 29 | 6:00PM | Cornerstone | vs. | Calvin College | 82-85 | (OT) |
| | Hall of Fame Tournament @ Hope |
| | | 7:30PM | Marygrove College | @ | Siena Heights | 53-70 | |
| | | 8:00PM | Aquinas | vs. | Hope College | 58-46 | |
| | GR Sports Hall of Fame Tournament--AQ wins 2d championship |
| December |
| | 1 | 7:00PM | Madonna | @ | Northwood University | 47-80 | |
| | 2 | 7:00PM | Goshen College | @ | Cornerstone | 86-85 | (2OT) |
| | | 7:30PM | Tri-State University | @ | Concordia | | |
| | | 7:30PM | Trine University | @ | Concordia | 61-71 | |
| | 3 | 7:00PM | Marygrove College | @ | UM-Dearborn | 67-66 | |
| | | 7:30PM | Davenport | @ | Trinity Christian College | 49-64 | |
| | | 7:30PM | Adrian College | @ | Siena Heights | 71-78 | |
| | 4 | 7:00PM | Indiana Wesleyan University | @ | UM-Dearborn | 81-61 | |
| | 5 | | Madonna | vs. | TBA | | |
| | WHAC/MIAA Challenge - Alma, Mich. - Dec. 5-6 |
| | | | Aquinas | vs. | TBA | | |
| | Georgetown College Classic |
| | | 6:00PM | Madonna | vs. | Olivet College | | |
| | WHAC/MIAA Challenge - Alma, Mich. - Dec. 5-6 |
| | | 7:30PM | Indiana Tech | vs. | Cardinal Stritch University | | |
| | Taylor University Tournament |
| | | 8:00PM | UM-Dearborn | @ | Alma College | | |
| | Alma College Tournament - Dec. 5-6 |
| | 6 | | Madonna | vs. | TBA | | |
| | WHAC/MIAA Challenge - Alma, Mich. - Dec. 5-6 |
| | | | Davenport | @ | Lindsey Wilson | | |
| | | | Indiana Tech | vs. | TBA | | |
| | Taylor University Tournament |
| | | | Aquinas | vs. | TBA | | |
| | Georgetown College Classic |
| | | 6:00PM | UM-Dearborn | @ | Olivet College | | |
| | Alma College Tournament - Dec. 5-6 |
| | | 7:30PM | Ohio Dominican College | @ | Siena Heights | | |
| | | 8:00PM | Madonna | @ | Alma College | | |
| | WHAC/MIAA Challenge - Alma, Mich. - Dec. 5-6 |
| | 8 | 7:30PM | Grace Bible College | @ | Davenport | | |
| | 9 | 7:00PM | Wilberforce University | @ | UM-Dearborn | | |
| | | 7:00PM | Indiana Tech | @ | Spring Arbor University | | |
| | 10 | | Davenport | @ | Calumet College of St. Joseph | | |
| | | 7:30PM | Calvin College | @ | Aquinas | | |
| | 12 | | Concordia | vs. | TBA | | |
| | Malone College Classic - Canton, Ohio |
| | | | Cornerstone | vs. | TBA | | |
| | Grace College Tournament |
| | | 6:00PM | Concordia | vs. | Walsh University | | |
| | Malone College Classic - Canton, Ohio |
| | | 8:00PM | Holy Cross College | @ | Madonna | | |
| | Mich. Educational Credit Union Tournament - Livonia, Mich. - Dec. 12-13 |
| | 13 | | Concordia | vs. | TBA | | |
| | Malone College Classic - Canton, Ohio |
| | | | TBA | @ | Madonna | | |
| | Mich. Educational Credit Union Tournament - Liovnia, Mich. - Dec. 12-13 |
| | | | Cornerstone | vs. | TBA | | |
| | Grace College Tournament |
| | | 3:00PM | Davenport | @ | Tri-State University | | |
| | | 3:00PM | Concordia | vs. | Malone College | | |
| | Malone College Classic - Canton, Ohio |
| | | 7:30PM | University of Saint Francis | @ | Siena Heights | | |
| | 16 | 1:00PM | Siena Heights | vs. | TBA | | |
| | St. Xavier Tournament |
| | 17 | 1:00PM | Siena Heights | vs. | TBA | | |
| | St. Xavier Tournament |
| | | 7:00PM | Madonna | @ | Notre Dame College | | |
| | | 7:30PM | Aquinas | @ | University of Detroit | | |
| | 18 | 1:00PM | Siena Heights | vs. | TBA | | |
| | St. Xavier Tournament |
| | 20 | 2:00PM | Hope College | @ | Aquinas | | |
| | | 3:00PM | Grace Bible College | @ | Cornerstone | | |
| | 22 | 7:00PM | St. Francis | @ | Aquinas | | |
| | | 7:00PM | Davenport | @ | Grace Bible College | | |
| | 27 | 1:00PM | Cornerstone | @ | Grace Bible College | | |
| | 28 | | Aquinas | vs. | TBA | | |
| | Ashland Tournament |
| | 29 | | Aquinas | vs. | TBA | | |
| | Ashland Tournament |
| | | 6:00PM | Madonna | vs. | Judson College | | |
| | Hope College Tournament - Holland, Mich. - Dec. 29-30 |
| | | 7:00PM | Davenport | @ | TBA | | |
| | Hope College Tournament - Dec. 29-30 |
| | 30 | | Madonna | vs. | TBA | | |
| | Hope College Tournament - Holland, Mich. - Dec. 29-30 |
| | | 7:00PM | Davenport | @ | TBA | | |
| | Hope College Tournament - Dec. 29-30 |
| | | 7:30PM | Valley City State University | vs. | Concordia | | |
| | Played at Warner Southern College - Lake Wales, Fla. |
| | | 7:30PM | Indiana University-South Bend | @ | Siena Heights | | |
| | 31 | | Concordia | @ | Warner Southern | | |
| | | 1:00PM | Indiana Tech | @ | Grace College | | |
| January |
| | 3 | 1:00PM | University of Saint Francis | @ | Indiana Tech | | |
| | | 3:00PM | Indiana University-South Bend | @ | Aquinas | | |
| | | 3:00PM | Madonna | @ | Marygrove College | | |
| | Game played at the University of Detroit Jesuit HS Arena |
| | | 3:00PM | Kuyper College | @ | Cornerstone | | |
| | | 7:30PM | University of Northwestern Ohio | @ | Siena Heights | | |
| * | 7 | 7:30PM | Siena Heights | @ | Aquinas | | |
| * | | 7:30PM | Cornerstone | @ | Concordia | | |
| * | | 7:30PM | Indiana Tech | @ | Madonna | | |
| * | | 7:30PM | UM-Dearborn | @ | Davenport | | |
| * | 10 | 3:00PM | Davenport | @ | Aquinas | | |
| * | | 3:00PM | Concordia | @ | Siena Heights | | |
| * | | 3:00PM | Cornerstone | @ | Madonna | | |
| * | | 3:00PM | UM-Dearborn | @ | Indiana Tech | | |
| | 12 | 7:00PM | Central State University | @ | UM-Dearborn | | |
| | | 7:00PM | Holy Cross College | @ | Indiana Tech | | |
| * | 14 | 7:00PM | Cornerstone | @ | UM-Dearborn | | |
| * | | 7:30PM | Aquinas | @ | Concordia | | |
| * | | 7:30PM | Madonna | @ | Siena Heights | | |
| * | | 7:30PM | Indiana Tech | @ | Davenport | | |
| * | 17 | 3:00PM | Aquinas | @ | Madonna | | |
| * | | 3:00PM | Davenport | @ | Concordia | | |
| * | | 3:00PM | Siena Heights | @ | UM-Dearborn | | |
| * | | 3:00PM | Indiana Tech | @ | Cornerstone | | |
| * | 19 | 7:30PM | Concordia | @ | Cornerstone | | |
| * | 21 | 7:00PM | Aquinas | @ | UM-Dearborn | | |
| * | | 7:30PM | Concordia | @ | Madonna | | |
| * | | 7:30PM | Cornerstone | @ | Davenport | | |
| * | | 7:30PM | Siena Heights | @ | Indiana Tech | | |
| * | 24 | 3:00PM | Madonna | @ | Davenport | | |
| * | | 3:00PM | UM-Dearborn | @ | Concordia | | |
| * | | 7:30PM | Cornerstone | @ | Siena Heights | | |
| * | | 8:00PM | Indiana Tech | @ | Aquinas | | |
| * | 28 | 7:30PM | Indiana Tech | @ | Concordia | | |
| * | | 7:30PM | Madonna | @ | UM-Dearborn | | |
| * | | 7:30PM | Davenport | @ | Siena Heights | | |
| * | | 8:00PM | Cornerstone | @ | Aquinas | | |
| | 30 | 3:00PM | Concordia | vs. | Concordia Wisconsin | | |
| | 59th Annual Concordia Invitational Tournament - Seward, Neb. |
| | 31 | | Concordia | vs. | TBA | | |
| | 59th Annual Concordia Invitational Tournament - Seward, Neb. |
| * | | 3:00PM | Madonna | @ | Indiana Tech | | |
| * | | 3:00PM | Davenport | @ | UM-Dearborn | | |
| * | | 7:30PM | Aquinas | @ | Siena Heights | | |
| February |
| | 2 | 7:00PM | Indiana Tech | @ | Holy Cross College | | |
| | | 7:00PM | UM-Dearborn | @ | Central State University | | |
| * | 4 | 7:00PM | Indiana Tech | @ | UM-Dearborn | | |
| * | | 7:30PM | Siena Heights | @ | Concordia | | |
| * | | 7:30PM | Madonna | @ | Cornerstone | | |
| * | | 8:00PM | Aquinas | @ | Davenport | | |
| | 5 | 7:00PM | Grace Bible College | @ | UM-Dearborn | | |
| * | 7 | 3:00PM | Concordia | @ | Aquinas | | |
| * | | 3:00PM | Siena Heights | @ | Madonna | | |
| * | | 3:00PM | Davenport | @ | Indiana Tech | | |
| * | | 3:00PM | UM-Dearborn | @ | Cornerstone | | |
| * | 11 | 7:00PM | UM-Dearborn | @ | Siena Heights | | |
| * | | 7:30PM | Concordia | @ | Davenport | | |
| * | | 7:30PM | Cornerstone | @ | Indiana Tech | | |
| * | | 8:00PM | Madonna | @ | Aquinas | | |
| * | 14 | 3:00PM | UM-Dearborn | @ | Aquinas | | |
| * | | 3:00PM | Madonna | @ | Concordia | | |
| * | | 3:00PM | Davenport | @ | Cornerstone | | |
| * | | 7:30PM | Indiana Tech | @ | Siena Heights | | |
| | 16 | 7:00PM | UM-Dearborn | @ | Rochester College | | |
| * | 18 | 3:00PM | Aquinas | @ | Indiana Tech | | |
| * | | 7:00PM | Concordia | @ | UM-Dearborn | | |
| * | | 7:30PM | Davenport | @ | Madonna | | |
| * | | 7:30PM | Siena Heights | @ | Cornerstone | | |
| * | 21 | 3:00PM | Aquinas | @ | Cornerstone | | |
| * | | 3:00PM | Concordia | @ | Indiana Tech | | |
| * | | 3:00PM | UM-Dearborn | @ | Madonna | | |
| * | | 3:00PM | Siena Heights | @ | Davenport | | |
| | 23 | 7:00PM | UM-Dearborn | @ | Marygrove College | | |
| | 26 | | Davenport | vs. | TBA | | |
| | WHAC Quarterfinals |
| | 28 | | Davenport | vs. | TBA | | |
| | WHAC Semifinals |
| March |
| | 3 | | Davenport | vs. | TBA | | |
| | WHAC Championship |
