| February |
| | 29 | 12:00PM | Madonna | vs. | John Carroll | 7-5 | (8) |
| | Tucson Invitational |
| | | 1:30PM | Indiana Tech | @ | Missouri Baptist College | RAIN | |
| | | Game 2 | Indiana Tech | @ | Missouri Baptist College | RAIN | |
| | | 5:00PM | Madonna | vs. | Briar Cliff University | 8-0 | (5) |
| | Tucson Invitational |
| March |
| | 1 | 9:30AM | Aquinas | vs. | Trinity International University | 10-4 | |
| | Tuscan Invitational |
| | | Game 2 | Aquinas | vs. | Trinity International University | 9-6 | |
| | | 11:00AM | Siena Heights | vs. | Johnson & Wales Univers | 13-0 | |
| | Gene Cusic Classic - Cape Coral, FL |
| | | 12:00PM | Indiana Tech | @ | Lindenwood University | 5-13 | |
| | | Game 2 | Indiana Tech | @ | Lindenwood University | 1-9 | |
| | | 1:00PM | Siena Heights | vs. | New York Institute of Technology | 3-5 | |
| | Gene Cusic Classic - Cape Coral, FL |
| | | 5:00PM | Madonna | vs. | Trinity International University | 6-2 | |
| | Tucson Invitational |
| | | 7:00PM | University of Great Falls | vs. | Madonna | 2-7 | |
| | Tucson, AZ Tourney |
| | 2 | 9:00AM | Siena Heights | vs. | St. Cloud State | 1-7 | |
| | Gene Cusic Classic - Fort Myers, FL |
| | | 11:00AM | Siena Heights | vs. | DeSales University | 2-5 | |
| | Gene Cusic Classic - Fort Myers, FL |
| | | 1:00PM | Siena Heights | vs. | New York Institute of Technology | 1-10 | |
| | Gene Cusic Classic - Fort Myers, FL |
| | | 3:00PM | Aquinas | vs. | Minot State University | 9-11 | |
| | Tucson Invitational |
| | | 4:00PM | Aquinas | vs. | William Penn College | 6-4 | |
| | Tuscan Invitational |
| | | 5:00PM | Madonna | vs. | Waynesburg College | 13-2 | |
| | Tucson Invitational |
| | | 5:00PM | Minot State University | vs. | Madonna | 3-12 | |
| | Tucson Invitational |
| | | 6:00PM | Aquinas | vs. | Peru State College | 11-7 | |
| | Tuscan Invitational |
| | 3 | 9:00AM | Siena Heights | vs. | DeSales University | 2-10 | |
| | Gene Cusic Classic - Cape Coral, FL |
| | | 11:00AM | Siena Heights | vs. | Eastern University | 6-0 | |
| | Gene Cusic Classic - Cape Coral, FL |
| | | 12:30PM | University of Great Falls | vs. | Madonna | 9-7 | |
| | Tucson, AZ Tourney |
| | | 5:00PM | William Penn College | vs. | Madonna | 6-1 | |
| | 4 | 11:30AM | Peru State College | vs. | Madonna | 1-0 | |
| | | 1:00PM | Siena Heights | vs. | Ursuline College | 8-0 | |
| | Gene Cusic Classic - Fort Myers, FL |
| | | 1:30PM | Trinity International University | vs. | Madonna | 6-19 | |
| | | 2:00PM | Aquinas | vs. | Minot State University | 6-0 | |
| | Tucson Invitational |
| | | 3:00PM | Ursuline College | vs. | Siena Heights | 2-1 | (8) |
| | Gene Cusic Classic - Fort Myers. FL |
| | | 3:00PM | Aquinas | vs. | University of Great Falls | 7-3 | |
| | Tuscan Invitational |
| | | 5:30PM | Aquinas | vs. | Dickinson State University | 4-12 | (6) |
| | Tuscan Invitational |
| | 5 | 11:00AM | Aquinas | vs. | Peru State College | 6-4 | |
| | Tuscan Invitational |
| | | 12:00PM | Dickinson State University | vs. | Madonna | 5-0 | |
| | | 1:00PM | Aquinas | vs. | Viterbo University | 11-1 | (5) |
| | Tuscan Invitational |
| | | 3:00PM | Mayville State University | vs. | Madonna | 0-6 | |
| | 6 | 11:00AM | Ursuline College | vs. | Siena Heights | 0-9 | |
| | Gene Cusic Classic - Fort Myers, FL |
| | | 11:00AM | Siena Heights | vs. | Saint Anselm College | 5-3 | |
| | Gene Cusic Classic - Cape Coral, FL |
| | 7 | 10:30AM | Aquinas | vs. | Mayville State University | 12-4 | (5) |
| | Tuscan Invitational |
| | | 12:30PM | Aquinas | vs. | Dickinson State University | 3-13 | |
| | Tuscan Invitational |
| | | 2:00PM | Siena Heights | @ | Webber International | 2-6 | |
| | | Game 2 | Siena Heights | @ | Webber International | 1-5 | |
| | 8 | 9:00AM | Indiana Tech | @ | Cumberland Univ. | RAIN | |
| | | Game 2 | Indiana Tech | @ | Cumberland Univ. | RAIN | |
| | | 1:00PM | Madonna | @ | Shawnee State University | RAIN | |
| | 9 | 9:00AM | Siena Heights | vs. | Edinboro University | 1-10 | |
| | Gene Cusic Classic - Cape Coral, FL |
| | | 11:00AM | Siena Heights | vs. | Edinboro University | 3-5 | |
| | Gene Cusic Classic - Cape Coral, FL |
| | | 12:00PM | Madonna | @ | University of Rio Grande | RAIN | |
| | | 2:00PM | Indiana Tech | @ | Cumberland College | RAIN | |
| | | Game 2 | Indiana Tech | @ | Cumberland College | RAIN | |
| | 10 | 1:30PM | Dickinson State University | vs. | Cornerstone | 10-3 | |
| | | 8:00PM | Iowa Wesleyan College | vs. | Cornerstone | 10-6 | |
| | 11 | 1:30PM | Purdue University-North Central | vs. | Cornerstone | 4-0 | |
| | | 3:00PM | Indiana Tech | @ | Urbana University | RAIN | |
| | | Game 2 | Indiana Tech | @ | Urbana University | RAIN | |
| | | 3:00PM | Concordia | @ | Spring Arbor University | RAIN | |
| | | Game 2 | Concordia | @ | Spring Arbor University | RAIN | |
| | | 4:00PM | Robert Morris College | vs. | Cornerstone | 6-3 | |
| | 12 | 11:30AM | Iowa Wesleyan College | vs. | Cornerstone | 9-8 | |
| | | 1:30PM | Purdue University-North Central | vs. | Cornerstone | 1-2 | |
| | | 3:00PM | Spring Arbor University | @ | Madonna | RAIN | |
| | | Game 2 | Spring Arbor University | @ | Madonna | RAIN | |
| | | 3:30PM | Kalamazoo College | @ | Aquinas | RAIN | |
| | 13 | 3:00PM | Indiana Tech | @ | Bluffton College | 1-10 | |
| | | Game 2 | Indiana Tech | @ | Bluffton College | 7-6 | (8) |
| | 14 | 1:30PM | Cornerstone | vs. | Calvin College | 7-2 | |
| | | 6:00PM | McKendree University | vs. | Cornerstone | 11-2 | |
| | 15 | 11:30AM | Mount Mercy College | vs. | Indiana Tech | 4-2 | |
| | | 1:00PM | Concordia | @ | Kalamazoo College | RAIN | |
| | | 1:00PM | Aquinas | @ | Malone College | RAIN | |
| | | Game 2 | Aquinas | @ | Malone College | RAIN | |
| | | Game 2 | Concordia | @ | Kalamazoo College | RAIN | |
| | | 1:00PM | Bethel College | @ | Madonna | RAIN | |
| | | Game 2 | Bethel College | @ | Madonna | RAIN | |
| | | 4:00PM | Jamestown College | vs. | Cornerstone | 6-2 | |
| | | 5:30PM | Indiana Tech | vs. | Concordia University-Wisconsin | 8-4 | |
| | NTC Tournament, Clermont, FL |
| | | 6:00PM | Dordt College | vs. | Cornerstone | 6-15 | |
| | 16 | 9:30AM | University of Rio Grande | vs. | Indiana Tech | 14-8 | |
| | | 11:00AM | Aquinas | @ | Walsh University | RAIN | |
| | | Game 2 | Aquinas | @ | Walsh University | RAIN | |
| | | 1:00PM | Concordia | @ | Adrian College | RAIN | |
| | | 1:30PM | Mount Mercy College | vs. | Indiana Tech | 2-6 | |
| | | Game 2 | Concordia | @ | Adrian College | RAIN | |
| | Rescheduled from March 16 |
| | 17 | 11:30AM | Dordt College | vs. | Cornerstone | 2-4 | |
| | | 2:00PM | Lubbock Christian | vs. | Cornerstone | 14-1 | |
| | 18 | 3:00PM | Concordia | @ | Indiana Wesleyan University | RAIN | |
| | | Game 2 | Concordia | @ | Indiana Wesleyan University | RAIN | |
| | 19 | 11:30AM | Indiana Tech | vs. | Morrisville State College | 10-7 | |
| | NTC Tournament, Clermont, FL |
| | | 3:00PM | Northwood University | @ | Madonna | RAIN | |
| | | Game 2 | Northwood University | @ | Madonna | RAIN | |
| | | 7:30PM | Clarke College | vs. | Indiana Tech | 2-1 | |
| | 20 | 9:30AM | Indiana Tech | vs. | Felician College | 2-1 | |
| | NTC Tournament, Clermont, FL |
| | | 1:30PM | Indiana Tech | vs. | University of Rio Grande | 6-1 | |
| | NTC Tournament, Clermont, FL |
| | | 3:30PM | Purdue University-North Central | @ | Concordia | | |
| | | 3:30PM | Concordia | @ | Purdue University-North Central | RAIN | |
| | | Game 2 | Concordia | @ | Purdue University-North Central | RAIN | |
| | 21 | 1:00PM | Aquinas | @ | Saint Xavier University | RAIN | |
| | | Game 2 | Aquinas | @ | Saint Xavier University | RAIN | |
| | 22 | | Aquinas | @ | Robert Morris College | RAIN | |
| | | Game 2 | Aquinas | @ | Robert Morris College | RAIN | |
| | | 3:30PM | Indiana Tech | vs. | Bethel University | 11-8 | |
| | NTC Tournament, Clermont, FL |
| | | Game 2 | Indiana Tech | vs. | Bethel University | 9-0 | |
| | Jessica Williams threw a 6 inning no-hit shut-out. |
| | 23 | 9:30AM | Indiana Tech | vs. | Buffalo State | 1-4 | |
| | NTC Tournament, Clermont, FL |
| | | Game 2 | Indiana Tech | vs. | Buffalo State | 2-8 | |
| | 25 | 3:00PM | UM-Dearborn | @ | University of Saint Francis | RAIN | |
| | | Game 2 | UM-Dearborn | @ | University of Saint Francis | RAIN | |
| | | 3:00PM | Saginaw Valley State University | @ | Madonna | RAIN | |
| | | Game 2 | Saginaw Valley State University | @ | Madonna | RAIN | |
| | | 3:00PM | Concordia | @ | Findlay University | 0-8 | |
| | | Game 2 | Concordia | @ | Findlay University | 5-7 | |
| | 26 | 3:00PM | Saint Joseph's College | @ | Indiana Tech | 3-2 | |
| | | Game 2 | Saint Joseph's College | @ | Indiana Tech | 14-1 | |
| | | 3:00PM | Cornerstone | @ | Bethel College | 0-1 | (8) |
| | | Game 2 | Cornerstone | @ | Bethel College | 1-9 | (6) |
| | | 3:30PM | Aquinas | @ | Ferris State University | RAIN | |
| | 27 | 3:00PM | Indiana Tech | @ | Marian College | RAIN | |
| | | Game 2 | Indiana Tech | @ | Marian College | RAIN | |
| | | 3:00PM | Concordia | @ | Adrian College | RAIN | |
| | Rescheduled from March 16 |
| | | 3:00PM | Madonna | @ | Huntington College | 1-1 | (7) |
| | Game called in 7th due to rain |
| | | Game 2 | Madonna | @ | Huntington College | RAIN | |
| | | Game 2 | Concordia | @ | Adrian College | RAIN | |
| | Rescheduled from March 16 |
| | 28 | 4:00PM | Madonna | @ | Lindsey Wilson | 1-3 | |
| | | Game 2 | Madonna | @ | Lindsey Wilson | 1-3 | |
| | 29 | | Siena Heights | @ | Cedarville University | 1-6 | |
| | Athletes in Action; Xenia, OH |
| | | Game 2 | Siena Heights | @ | Cedarville University | 0-8 | (6) |
| | | 11:30AM | Midway College | vs. | Madonna | 0-10 | |
| | MU's Jess Irwin first no-hitter with 17 K's |
| * | | 1:00PM | UM-Dearborn | @ | Aquinas | 1-4 | |
| * | | Game 2 | UM-Dearborn | @ | Aquinas | 8-6 | |
| | | 1:30PM | Madonna | @ | Campbellsville University | 1-7 | |
| | 30 | 10:30AM | Madonna | @ | Lindsey Wilson | 4-3 | |
| | | 12:30PM | Campbellsville University | vs. | Madonna | 6-0 | |
| | | 1:00PM | University of Saint Francis | @ | Concordia | | |
| | | 1:00PM | Concordia | @ | University of Saint Francis | RAIN | |
| | | Game 2 | Concordia | @ | University of Saint Francis | RAIN | |
| * | | 1:00PM | Aquinas | @ | Indiana Tech | 1-9 | |
| * | | Game 2 | Aquinas | @ | Indiana Tech | 8-3 | |
| April |
| | 1 | 3:00PM | Rochester College | @ | Concordia | RAIN | |
| | | 3:00PM | Indiana Tech | @ | Grace College | RAIN | |
| | | Game 2 | Indiana Tech | @ | Grace College | RAIN | |
| | | Game 2 | Rochester College | @ | Concordia | RAIN | |
| | | 4:00PM | Siena Heights | @ | Huntington College | RAIN | |
| | Rescheduled from March 14th |
| | | Game 2 | Siena Heights | @ | Huntington College | RAIN | |
| | Rescheduled from March 14th |
| * | 2 | 2:00PM | Cornerstone | @ | Aquinas | 4-5 | (8) |
| * | | Game 2 | Cornerstone | @ | Aquinas | 3-2 | |
| * | | 3:00PM | Concordia | @ | Siena Heights | 7-10 | |
| * | | Game 2 | Concordia | @ | Siena Heights | 1-9 | |
| * | | 3:00PM | Madonna | @ | UM-Dearborn | 1-2 | |
| * | | Game 2 | Madonna | @ | UM-Dearborn | 14-1 | |
| | 3 | 3:00PM | Indiana Wesleyan University | @ | Indiana Tech | 3-0 | |
| | | Game 2 | Indiana Wesleyan University | @ | Indiana Tech | 6-5 | (8) |
| * | | 4:00PM | Madonna | @ | Siena Heights | 6-0 | |
| | Rescheduled from 3/22 |
| * | | Game 2 | Madonna | @ | Siena Heights | 15-4 | |
| | Rescheduled from 3/22 |
| | 4 | 3:00PM | University of Saint Francis | @ | Indiana Tech | RAIN | |
| | | Game 2 | University of Saint Francis | @ | Indiana Tech | RAIN | |
| | | 3:30PM | UM-Dearborn | @ | Hillsdale College | 1-5 | |
| | | Game 2 | UM-Dearborn | @ | Hillsdale College | 3-11 | |
| * | 5 | 1:00PM | Indiana Tech | @ | Concordia | 5-0 | |
| * | | 1:00PM | Cornerstone | @ | Siena Heights | 6-3 | |
| * | | Game 2 | Cornerstone | @ | Siena Heights | 11-2 | |
| * | | 1:00PM | Aquinas | @ | Madonna | 4-10 | |
| * | | Game 2 | Aquinas | @ | Madonna | 0-8 | (5) |
| * | | Game 2 | Indiana Tech | @ | Concordia | 6-4 | (8) |
| * | 6 | 1:00PM | Concordia | @ | UM-Dearborn | 0-8 | (5) |
| * | | 1:00PM | Siena Heights | @ | Indiana Tech | 1-5 | |
| * | | Game 2 | Siena Heights | @ | Indiana Tech | 7-8 | |
| * | | Game 2 | Concordia | @ | UM-Dearborn | 0-12 | (5) |
| | 7 | 1:00PM | Siena Heights | @ | Indiana Wesleyan University | 2-10 | |
| | Rescheduled from March 15th |
| | | Game 2 | Siena Heights | @ | Indiana Wesleyan University | 4-5 | |
| | Rescheduled from March 15th |
| | | 3:30PM | Cornerstone | @ | Ferris State University | 0-5 | |
| | | Game 2 | Cornerstone | @ | Ferris State University | 2-13 | |
| | 8 | | University of Saint Francis | @ | Concordia | 7-1 | |
| | Rescheduled from March 30 |
| | | Game 2 | University of Saint Francis | @ | Concordia | 8-0 | (6) |
| | | 3:00PM | Spring Arbor University | @ | UM-Dearborn | 7-11 | |
| | | Game 2 | Spring Arbor University | @ | UM-Dearborn | 4-1 | |
| | | 3:00PM | Trinity Christian College | @ | Cornerstone | 5-6 | (8) |
| | | Game 2 | Trinity Christian College | @ | Cornerstone | 4-7 | |
| | 9 | 3:00PM | Madonna | @ | Rochester College | 4-1 | |
| | | Game 2 | Madonna | @ | Rochester College | 3-2 | |
| * | | 3:00PM | Aquinas | @ | Concordia | 11-0 | (5) |
| * | | 3:00PM | UM-Dearborn | @ | Siena Heights | 1-4 | |
| * | | Game 2 | UM-Dearborn | @ | Siena Heights | 0-1 | (10) |
| * | | Game 2 | Aquinas | @ | Concordia | 8-6 | |
| | 10 | 3:00PM | Siena Heights | @ | Tiffin University | RAIN | |
| | | Game 2 | Siena Heights | @ | Tiffin University | RAIN | |
| | | 3:00PM | Aquinas | @ | Calvin College | RAIN | |
| | | Game 2 | Aquinas | @ | Calvin College | RAIN | |
| * | 11 | 3:00PM | Indiana Tech | @ | Madonna | 1-9 | (5) |
| * | | Game 2 | Indiana Tech | @ | Madonna | 1-0 | |
| * | | 3:00PM | Cornerstone | @ | Concordia | 1-0 | (8) |
| * | | Game 2 | Cornerstone | @ | Concordia | 1-0 | |
| | | 3:30PM | Siena Heights | @ | Adrian College | 1-6 | |
| | Rescheduled from 3/12 & 3/19 & 3/30 |
| * | 12 | 1:00PM | Indiana Tech | @ | UM-Dearborn | 8-6 | |
| * | | Game 2 | Indiana Tech | @ | UM-Dearborn | 5-10 | |
| * | | 1:00PM | Concordia | @ | Madonna | 0-6 | |
| * | | Game 2 | Concordia | @ | Madonna | 0-7 | |
| | Concordia forfeited game two |
| * | 13 | 1:00PM | Aquinas | @ | UM-Dearborn | RAIN | |
| * | | Game 2 | Aquinas | @ | UM-Dearborn | RAIN | |
| * | 14 | 3:00PM | Indiana Tech | @ | Cornerstone | 7-0 | |
| * | | Game 2 | Indiana Tech | @ | Cornerstone | 13-3 | |
| * | | 3:00PM | Siena Heights | @ | Aquinas | 1-10 | (5) |
| * | | Game 2 | Siena Heights | @ | Aquinas | 2-4 | |
| * | 15 | 3:00PM | Aquinas | @ | UM-Dearborn | 10-4 | |
| | Rescheduled from April 13 |
| | | 3:00PM | Concordia | @ | Adrian College | 3-4 | |
| | Rescheduled from March 27 |
| | | Game 2 | Concordia | @ | Adrian College | 0-8 | |
| | | 4:00PM | University of Saint Francis | @ | Siena Heights | 4-8 | |
| | rescheduled from 3/20 |
| | | Game 2 | University of Saint Francis | @ | Siena Heights | 2-7 | |
| * | | Game 2 | Aquinas | @ | UM-Dearborn | 3-4 | |
| * | 16 | 3:00PM | Siena Heights | @ | Madonna | 0-8 | (5) |
| | MU's Jess Irwin throws a no-hitter |
| * | | Game 2 | Siena Heights | @ | Madonna | 7-5 | |
| * | | 3:00PM | Indiana Tech | @ | Aquinas | 1-6 | |
| * | | Game 2 | Indiana Tech | @ | Aquinas | 0-5 | |
| * | | 3:00PM | UM-Dearborn | @ | Cornerstone | 1-2 | |
| * | | Game 2 | UM-Dearborn | @ | Cornerstone | 5-3 | |
| * | 17 | Game 2 | Concordia | @ | Cornerstone | 0-6 | |
| * | | 3:00PM | Concordia | @ | Cornerstone | 6-3 | |
| | Cardinals win 1st game of the Season |
| * | 18 | 3:00PM | Madonna | @ | Indiana Tech | 3-1 | |
| * | | 3:00PM | Cornerstone | @ | UM-Dearborn | 4-5 | |
| | |
| * | | Game 2 | Cornerstone | @ | UM-Dearborn | 2-0 | |
| * | | Game 2 | Madonna | @ | Indiana Tech | 4-2 | |
| * | 19 | 1:00PM | UM-Dearborn | @ | Madonna | 0-10 | (5) |
| | Head coach Al White wins his 300th career game |
| * | | Game 2 | UM-Dearborn | @ | Madonna | 5-6 | (10) |
| * | | Game 2 | Siena Heights | @ | Concordia | 15-3 | (5) |
| * | | 1:00PM | Aquinas | @ | Cornerstone | 10-2 | |
| * | | Game 2 | Aquinas | @ | Cornerstone | 6-5 | |
| | | 1:00PM | Tiffin University | @ | Indiana Tech | 7-7 | |
| | Game ended in bottom of 6th, 1 out with 2 runners on due to rain |
| | | Game 2 | Tiffin University | @ | Indiana Tech | RAIN | |
| * | | 1:00PM | Siena Heights | @ | Concordia | 11-2 | (5) |
| * | 20 | 1:00PM | Concordia | @ | Indiana Tech | 0-8 | |
| | | 1:00PM | Rochester College | @ | UM-Dearborn | 0-4 | |
| | | Game 2 | Rochester College | @ | UM-Dearborn | 3-2 | |
| * | | 1:00PM | Madonna | @ | Aquinas | 5-0 | |
| * | | Game 2 | Madonna | @ | Aquinas | 9-10 | |
| * | | Game 2 | Concordia | @ | Indiana Tech | 0-5 | |
| | 21 | 4:00PM | Rochester College | @ | Siena Heights | 1-7 | |
| | Rescheduled from previous rainouts |
| | | Game 2 | Rochester College | @ | Siena Heights | 7-6 | |
| * | 22 | 3:00PM | Siena Heights | @ | Cornerstone | 2-3 | |
| * | | Game 2 | Siena Heights | @ | Cornerstone | 6-8 | |
| | | 3:30PM | Oberlin College | @ | Concordia | 3-1 | |
| | | Game 2 | Oberlin College | @ | Concordia | 3-12 | (5) |
| * | 23 | 3:00PM | UM-Dearborn | @ | Concordia | 13-8 | (8) |
| * | | 3:00PM | Indiana Tech | @ | Siena Heights | 6-1 | |
| * | | Game 2 | Indiana Tech | @ | Siena Heights | 12-5 | |
| | | 3:00PM | Rochester College | @ | Cornerstone | 0-8 | (5) |
| | | Game 2 | Rochester College | @ | Cornerstone | 4-3 | (8) |
| * | | 3:00PM | UM-Dearborn | @ | Concordia | 5-2 | |
| * | 25 | 3:00PM | Madonna | @ | Cornerstone | 8-3 | |
| * | | Game 2 | Madonna | @ | Cornerstone | 4-3 | |
| * | | 3:00PM | UM-Dearborn | @ | Indiana Tech | 1-4 | |
| * | | 4:00PM | Aquinas | @ | Siena Heights | 12-3 | (5) |
| * | | Game 2 | Aquinas | @ | Siena Heights | 14-4 | (6) |
| * | | Game 2 | UM-Dearborn | @ | Indiana Tech | 4-7 | |
| * | 26 | 1:00PM | Concordia | @ | Aquinas | 1-8 | |
| * | | 1:00PM | Siena Heights | @ | UM-Dearborn | 1-5 | |
| * | | Game 2 | Siena Heights | @ | UM-Dearborn | 4-3 | (8) |
| * | | 1:00PM | Cornerstone | @ | Indiana Tech | 3-5 | |
| * | | Game 2 | Cornerstone | @ | Indiana Tech | 9-2 | |
| * | | Game 2 | Concordia | @ | Aquinas | 2-11 | |
| * | 27 | 1:00PM | Madonna | @ | Concordia | 5-0 | |
| * | | Game 2 | Madonna | @ | Concordia | 6-0 | |
| * | 28 | 3:00PM | Cornerstone | @ | Madonna | 0-8 | (5) |
| | Reschedule from April 4th. |
| * | | Game 2 | Cornerstone | @ | Madonna | 0-12 | (5) |
| | | 3:30PM | Kalamazoo College | @ | Aquinas | 1-8 | |
| | Rescheduled from March 12 |
| | | Game 2 | Kalamazoo College | @ | Aquinas | 3-11 | (5) |
| | End regular season |
| | 30 | 10:00AM | UM-Dearborn | @ | Madonna | 0-8 | (5) |
| | WHAC Tournament - First Round Game |
| | | 12:00PM | Aquinas | vs. | Indiana Tech | 6-10 | |
| | WHAC Tournament - First Round Game |
| | | 2:00PM | Aquinas | vs. | UM-Dearborn | 5-4 | (8) |
| | WHAC Tournament - UM-Dearborn Eliminated |
| | | 4:00PM | Indiana Tech | @ | Madonna | 0-4 | |
| | WHAC Tournament - Game 4 |
| May |
| | 1 | 12:00PM | Aquinas | vs. | Indiana Tech | 12-4 | (5) |
| | Game five of WHAC Tournament |
| | | 2:00PM | Aquinas | @ | Madonna | 1-7 | |
| | Madonna wins 2008 WHAC Tournament Title |
| | 6 | 12:00PM | Aquinas | vs. | Huntington College | 6-0 | |
| | NAIA Region VIII Tournament - Rd. 1 |
| | | 12:00PM | Indiana Tech | vs. | Spring Arbor University | 8-1 | |
| | NAIA Region VIII Tournament - Rd. 1 |
| | | 2:00PM | Madonna | vs. | Indiana Tech | 6-1 | |
| | NAIA Region VIII Tournament |
| | | 2:00PM | Aquinas | vs. | Bethel College | 1-4 | |
| | NAIA Softball Regional |
| | | 4:00PM | Aquinas | vs. | Spring Arbor University | 0-4 | |
| | NAIA Softball Regional |
| | | 4:00PM | Indiana Tech | vs. | Huntington College | 4-2 | (8) |
| | NAIA Region VIII Tournament |
| | 7 | 10:00AM | Indiana Tech | vs. | Spring Arbor University | 8-7 | |
| | NAIA Region VIII Tournament - Tech advances to play Madonna on 5/8 |
| | | 10:00AM | Madonna | @ | Bethel College | 3-5 | (8) |
| | NAIA Region VIII |
| | 8 | 10:00AM | Indiana Tech | vs. | Madonna | 0-5 | |
| | NAIA Region VIII Tournament |
| | | 12:00PM | Madonna | vs. | Bethel College | 1-5 | |
| | NAIA Region VIII Championship Game |
