| November |
| | 1 | 7:00PM | Rochester College | @ | UM-Dearborn | 47-88 | |
| | 2 | 6:00PM | Concordia | @ | University of Saint Francis | 2-0 | |
| | St. Francis Classic |
| | | 7:30PM | St. Mary-of-the-Woods College | @ | Cornerstone | 38-93 | |
| | CU Classic |
| | 3 | 1:00PM | Concordia | vs. | Taylor University-Ft. Wayne | 94-60 | |
| | St. Francis Classic |
| | | 3:00PM | Marygrove College | @ | Cornerstone | 48-82 | |
| | CU Classic |
| | | 3:00PM | Spring Arbor University | @ | Siena Heights | 57-73 | |
| | | 7:00PM | Indiana University-South Bend | @ | UM-Dearborn | 76-67 | |
| | 5 | 5:00PM | UM-Dearborn | @ | Kuyper College | 88-31 | |
| | 6 | 7:00PM | Madonna | @ | Purdue University Calumet | 82-73 | |
| | 7 | 7:00PM | Huntington College | @ | Indiana Tech | 67-47 | |
| | 8 | 7:00PM | Indiana Tech | @ | Goshen College | 50-66 | |
| | | 7:00PM | Spring Arbor University | @ | Davenport | 57-69 | |
| | | 7:00PM | Aquinas | @ | Grace College | 86-44 | |
| | Date correction |
| | 9 | | Madonna | vs. | Lindsey Wilson | 68-78 | |
| | Campbellsville Univ. Tournament - Campbellsville, Kent. |
| | | 7:00PM | Siena Heights | @ | Urbana University | 57-80 | |
| | 10 | | Madonna | @ | Campbellsville University | 41-81 | |
| | Campbellsville Univ. Tournament - Campbellsville, Kent. |
| | | 1:00PM | Indiana Tech | @ | Taylor University | 34-67 | |
| | | 1:00PM | Indiana University-South Bend | @ | Concordia | 72-52 | |
| | | 1:00PM | Goshen College | @ | Aquinas | 56-80 | |
| | | 4:00PM | Davenport | @ | University of Saint Francis | 82-63 | |
| | #12 Davenport Upsets #2 Univ. of St. Francis (IN) |
| | | 5:00PM | Walsh University | @ | Cornerstone | 56-63 |  |
| | 13 | 5:00PM | UM-Dearborn | @ | Grace Bible College | 75-71 | |
| | | 6:00PM | Indiana Tech | @ | University of Rio Grande | 34-93 | |
| | | 7:00PM | Cornerstone | @ | Spring Arbor University | 59-65 | |
| | | 7:00PM | Purdue University Calumet | @ | Davenport | 62-97 | |
| | | 8:00PM | Aquinas | @ | Huntington College | 67-62 | |
| | 14 | 7:00PM | Siena Heights | @ | Goshen College | 63-73 | |
| | 16 | 8:00PM | Trinity International University | @ | Aquinas | 49-92 | |
| | Aquinas College Classic |
| | 17 | 1:00PM | University of Saint Francis | @ | Cornerstone | 0-2 | |
| | Forfeit |
| | | 3:00PM | Siena Heights | @ | Defiance College | 66-76 | |
| | | 3:00PM | Spring Arbor University | @ | Aquinas | 53-64 | |
| | Aquinas College Classic |
| | | 7:00PM | Indiana Tech | @ | Ohio Dominican College | 46-95 | |
| | | 7:00PM | Davenport | @ | Columbia Union College | 95-89 | |
| | Panthers Defeat NCAA Div. II Team |
| | 20 | 6:00PM | Cornerstone | @ | Goshen College | 74-44 | |
| | | 7:00PM | Robert Morris College | @ | Indiana Tech | 79-42 | |
| | | 7:00PM | Madonna | @ | Spring Arbor University | 55-68 | |
| | | 7:00PM | Calvin College | @ | Concordia | 59-52 | |
| | | 7:00PM | Aquinas | @ | Alma College | 75-56 | |
| | | 7:30PM | Adrian College | @ | Siena Heights | 51-65 | |
| | 23 | 6:00PM | Aquinas | vs. | Rochester College | 99-51 | |
| | Olivet College Classic |
| | | 8:00PM | Concordia | @ | Olivet College | 60-69 | |
| | Olivet Comet Classic |
| | 24 | 1:00PM | Madonna | @ | Wayne State University | 52-90 | |
| | | 1:00PM | Siena Heights | @ | Huntington College | 53-73 | |
| | | 1:00PM | Concordia | vs. | Rochester College | 87-45 | |
| | Olivet Comet Classic |
| | | 3:00PM | Aquinas | @ | Olivet College | 77-56 | |
| | Olivet College Classic-final round |
| | | 7:30PM | Davenport | vs. | University of Wisconsin-Platteville | 73-62 | |
| | @ Cardinal Stritch |
| | 25 | | Davenport | @ | Cardinal Stritch University | 85-78 | |
| | 27 | 6:00PM | Concordia | @ | Alma College | 64-62 | |
| | | 7:00PM | Indiana Tech | @ | Bethel College | 57-78 | |
| | | 7:00PM | Trinity Christian College | @ | Cornerstone | 62-80 | |
| | | 7:00PM | UM-Dearborn | vs. | Rochester College | 62-42 | |
| | | 7:30PM | Grace College | @ | Siena Heights | 63-69 | (OT) |
| | 29 | 5:30PM | Andrews University | @ | UM-Dearborn | 37-95 | |
| | | 7:00PM | Indiana University-South Bend | @ | Indiana Tech | 79-31 | |
| | | 7:00PM | Siena Heights | @ | Alma College | 66-53 | |
| | 30 | 2:00PM | Davenport | vs. | Northwestern College | 74-37 | |
| | Judson College Tournament - Nov. 30 - Dec. 1 |
| | | 5:00PM | Cornerstone | vs. | Valley City State University | 70-49 | |
| | Trinity International Tournament |
| | | 6:00PM | Concordia | @ | Mount Vernon Nazarene College | 61-89 | |
| | Ohio Dominican University Classic - Second Round |
| December |
| | 1 | 1:00PM | Indiana Tech | @ | Indiana Wesleyan University | 38-96 | |
| | | 1:00PM | Purdue University Calumet | @ | Siena Heights | 69-78 | |
| | | 1:00PM | Marygrove College | @ | UM-Dearborn | 65-59 | |
| | | 1:00PM | Aquinas | @ | Spring Arbor University | 70-53 | |
| | | 4:00PM | Concordia | @ | Ohio Dominican College | 63-81 | |
| | Ohio Dominican Classic |
| | | 5:00PM | Cornerstone | vs. | Grace College | 59-45 | |
| | Trinity International Tournament Championship |
| | | 5:00PM | Davenport | @ | Judson College | 63-41 | |
| | Judson College Tournament - Nov. 30 - Dec. 1 |
| | 4 | 6:00PM | Indiana University-South Bend | @ | Cornerstone | 65-68 | (OT) |
| | | 7:00PM | Siena Heights | @ | Grace Bible College | 93-56 | |
| | 5 | 7:00PM | Grace College | @ | Indiana Tech | 70-56 | |
| | | 7:00PM | Judson College | @ | Aquinas | 60-79 | |
| | AQ ranked 14th in Division II; win streak at 10 |
| | 6 | 5:30PM | UM-Dearborn | @ | Andrews University | 88-33 | |
| | | 7:00PM | Rochester College | @ | Concordia | 48-90 | |
| | 7 | 7:00PM | Indiana Tech | @ | Wilberforce University | 66-75 | |
| | | 7:00PM | Cornerstone | @ | Purdue University Calumet | 76-49 | |
| | 8 | 12:00PM | Davenport | @ | Indiana University-South Bend | 74-84 | |
| | | 1:00PM | University of Saint Francis | @ | Aquinas | 76-67 | |
| | | 3:00PM | Cornerstone | @ | Cardinal Stritch University | 63-68 | |
| | | 3:00PM | UM-Dearborn | @ | Wilberforce University | 63-82 | |
| | | 3:30PM | Urbana University | @ | Indiana Tech | 66-64 | |
| | | 7:30PM | Madonna | @ | Goshen College | 60-67 | |
| | 9 | | Siena Heights | @ | Robert Morris College | 57-73 | |
| | 10 | 5:00PM | Davenport | @ | Grace Bible College | 92-72 | |
| | 12 | 7:00PM | Indiana Tech | @ | Urbana University | 44-69 | |
| | | 7:30PM | Madonna | @ | Albion College | 60-88 | |
| | 14 | | Madonna | @ | Bethel College | 54-74 | |
| | WHAC/MCC Challenge - Mishawaka, Ind. |
| | | 8:00PM | Indiana Wesleyan University | vs. | Cornerstone | 51-50 | |
| | MCC/WHAC Challenge |
| | | 8:00PM | Institute of Technology West Virginia Un | @ | Indiana Tech | 73-63 | |
| | Sport One Tournament |
| | | 9:00PM | Davenport | vs. | Bethel College | 68-60 | |
| | Trinity Christian Classic - Dec. 14 - Dec. 15 |
| | 15 | | Madonna | vs. | Indiana Wesleyan University | 42-62 | |
| | WHAC/MCC Challenge - Mishawaka, Ind. |
| | | 1:00PM | Walsh University | @ | Siena Heights | 39-51 | |
| | | 1:00PM | UM-Dearborn | @ | Ohio State-Marion | RAIN | |
| | Postponed due to weather |
| | | 1:00PM | Concordia | @ | Spring Arbor University | 67-71 | (OT) |
| | | 2:00PM | University of Rio Grande | @ | Indiana Tech | 75-32 | |
| | Sport One Tournnament |
| | | 3:00PM | Cornerstone | @ | Bethel College | 68-75 | |
| | MCC/WHAC Challenge |
| | | 3:00PM | Davenport | @ | Trinity Christian College | 57-63 | |
| | Trinity Christian Classic - Dec. 14 - Dec. 15 |
| | 18 | 5:30PM | Siena Heights | vs. | University of Rio Grande | 73-82 | |
| | Daemon College Tournament - Dec 18-19 |
| | 19 | | Siena Heights | vs. | Grace College | 73-65 | |
| | Daemon College Tournament - Dec 18-19 |
| | | 7:00PM | Olivet College | @ | Madonna | 54-62 | |
| | MU wins 2007-08 home opener |
| | | 7:00PM | Calumet College of St. Joseph | @ | Davenport | 32-98 | |
| | 21 | 2:00PM | UM-Dearborn | @ | Purdue University Calumet | 90-81 | |
| | | 6:00PM | Aquinas | vs. | Bethel College | 63-57 | |
| | USF Lady Cougar Classic (Dec. 21-22): AQ t18, Bethel 5th |
| | | 7:00PM | Rochester College | @ | Madonna | 31-65 | |
| | Caryn Inman posts double-double with 14 pts. and 10 rebounds to go along with six steals and four assists |
| | 22 | 4:00PM | Aquinas | @ | University of Saint Francis | 2-0 | |
| | USF Lady Cougar Classic: USF forfeit (negates 80-71 win) |
| | 27 | 1:00PM | Madonna | @ | Warner Southern | 62-60 | |
| | Warner Southern Tournament - Lake Wales, Fla. |
| | 28 | | Davenport | vs. | University of Illinois at Springfield | 91-88 | |
| | Clarke College Holiday Tournament - Dec. 28-Dec. 31 |
| | | 3:00PM | Madonna | vs. | Indiana Wesleyan University | 42-48 | |
| | At Warner Southern Hampton Inn Classic |
| | | 6:00PM | Aquinas | vs. | Olivet Nazarene University | 81-124 | |
| | Taylor Holiday Classic--sets AQ record for points allowed; ONU 24th in NAIA DI |
| | | 8:00PM | Cornerstone | @ | Taylor University | 61-68 | |
| | Taylor Classic |
| | 29 | 12:00PM | Cornerstone | vs. | Olivet Nazarene University | 78-106 | |
| | Taylor Classic |
| | | 1:00PM | Rochester College | @ | Siena Heights | 41-82 | |
| | | 1:00PM | Concordia | @ | Concordia University-Austin | 57-70 | |
| | | 2:00PM | Aquinas | @ | Taylor University | 86-70 | |
| | Taylor Holiday Classic |
| | | 6:00PM | Madonna | vs. | Cedarville University | 53-46 | |
| | Warner Southern Tournament - Lake Wales, Fla. |
| | | 6:00PM | UM-Dearborn | @ | Marian College | 51-64 | |
| | Marian College Invitational |
| | 30 | 1:00PM | UM-Dearborn | vs. | Indiana University-South Bend | 53-89 | |
| | Marian College Invitational |
| | | 2:00PM | Concordia | @ | Texas Lutheran | 72-48 | |
| | | 6:30PM | Davenport | vs. | Robert Morris College | 71-75 | |
| | Clarke College Holiday Tournament - Dec. 28-Dec. 31 |
| | 31 | 12:00PM | Davenport | @ | Clarke College | 93-69 | |
| | Clarke College Holiday Tournament - Dec. 28-Dec. 31 |
| January |
| | 3 | 7:00PM | Calumet College of St. Joseph | @ | Concordia | 39-72 | |
| * | 5 | 1:00PM | Indiana Tech | @ | Madonna | 60-69 | |
| | Christie Carrico scores a career high 29 points and grabs 10 rebounds in MU's win |
| * | | 1:00PM | Aquinas | @ | Cornerstone | 73-77 | (2OT) |
| | CU defeats #18 AQ |
| * | | 1:00PM | Concordia | @ | Davenport | 53-82 | |
| * | | 1:00PM | Siena Heights | @ | UM-Dearborn | 81-77 | |
| | 7 | 5:00PM | Kuyper College | @ | UM-Dearborn | 22-76 | |
| * | 9 | 5:30PM | Cornerstone | @ | UM-Dearborn | 77-61 | |
| * | | 7:30PM | Indiana Tech | @ | Concordia | 46-75 | |
| * | | 7:30PM | Madonna | @ | Aquinas | 51-63 | |
| * | | 7:30PM | Davenport | @ | Siena Heights | 76-67 | |
| * | 12 | 1:00PM | Davenport | @ | Indiana Tech | 94-59 | |
| * | | 1:00PM | Siena Heights | @ | Cornerstone | 59-74 | |
| * | | 1:00PM | Madonna | @ | UM-Dearborn | 76-63 | |
| * | | 1:00PM | Aquinas | @ | Concordia | 54-41 | |
| | 14 | 7:30PM | Ohio State-Marion | @ | UM-Dearborn | 17-85 | |
| * | 16 | 6:00PM | Aquinas | @ | Davenport | 64-81 | |
| * | | 7:30PM | Siena Heights | @ | Indiana Tech | 73-74 | |
| * | | 7:30PM | Cornerstone | @ | Madonna | 62-58 | |
| * | | 7:30PM | UM-Dearborn | @ | Concordia | 54-61 | |
| * | 19 | 1:00PM | Indiana Tech | @ | Aquinas | 54-94 | |
| * | | 1:00PM | Concordia | @ | Cornerstone | 50-61 | |
| * | | 1:00PM | Madonna | @ | Siena Heights | 78-69 | |
| * | | 1:00PM | Davenport | @ | UM-Dearborn | 72-61 | |
| | 21 | 5:00PM | Grace Bible College | @ | UM-Dearborn | 58-61 | |
| * | 23 | 5:30PM | UM-Dearborn | @ | Indiana Tech | 71-59 | |
| * | | 5:30PM | Davenport | @ | Cornerstone | 77-69 | |
| * | | 7:30PM | Concordia | @ | Madonna | 64-74 | (OT) |
| * | | 7:30PM | Siena Heights | @ | Aquinas | 81-78 | |
| | 25 | 1:00PM | Concordia | vs. | Concordia University-Wisconsin | 58-51 | |
| | Cards come back from 12-0 deficit; Play in first CIT Championship |
| * | 26 | 1:00PM | Madonna | @ | Davenport | 70-74 | |
| * | | 1:00PM | Aquinas | @ | UM-Dearborn | 67-64 | |
| * | | 3:00PM | Cornerstone | @ | Indiana Tech | 79-42 | |
| | | 5:00PM | Concordia | vs. | Concordia University | 55-75 | |
| | Concordia Invitational Tournament Championship Game |
| * | 28 | 7:30PM | Siena Heights | @ | Concordia | 72-64 | |
| * | 30 | 5:30PM | Cornerstone | @ | Aquinas | 60-57 | |
| * | | 7:00PM | Davenport | @ | Concordia | 74-53 | |
| * | | 7:30PM | Madonna | @ | Indiana Tech | 66-43 | |
| * | | 7:30PM | UM-Dearborn | @ | Siena Heights | 52-65 | |
| | 31 | 5:30PM | UM-Dearborn | @ | Ohio State-Marion | 78-38 | |
| | Rescheduled game from Dec. 15 |
| February |
| * | 2 | 1:00PM | UM-Dearborn | @ | Cornerstone | 47-73 | |
| * | | 1:00PM | Aquinas | @ | Madonna | 78-66 | |
| * | | 1:00PM | Siena Heights | @ | Davenport | 60-84 | |
| | Panthers win 10th straight overall |
| * | | 3:00PM | Concordia | @ | Indiana Tech | 68-49 | |
| * | 6 | 5:30PM | UM-Dearborn | @ | Madonna | 60-67 | |
| | | 7:30PM | Indiana Tech | @ | Davenport | RAIN | |
| | Game cancelled due to inclement weather - make-up scheduled for Feb. 23 |
| * | | 7:30PM | Cornerstone | @ | Siena Heights | RAIN | |
| | Game cancelled due to inclement weather - make-up scheduled for Feb. 23 |
| * | 9 | 1:00PM | Madonna | @ | Cornerstone | 59-67 | |
| * | | 1:00PM | Davenport | @ | Aquinas | 101-91 | |
| * | | 1:00PM | Concordia | @ | UM-Dearborn | 69-56 | |
| * | | 3:00PM | Indiana Tech | @ | Siena Heights | 59-72 | |
| | 11 | 5:30PM | University of Northwestern Ohio | @ | Indiana Tech | 68-55 | |
| * | 13 | 5:30PM | Aquinas | @ | Indiana Tech | 68-49 | |
| * | | 6:00PM | UM-Dearborn | @ | Davenport | 64-85 | |
| * | | 7:30PM | Cornerstone | @ | Concordia | 67-53 | |
| * | | 7:30PM | Siena Heights | @ | Madonna | 45-50 | |
| * | 16 | 1:00PM | Indiana Tech | @ | UM-Dearborn | 52-89 | |
| * | | 1:00PM | Cornerstone | @ | Davenport | 69-68 | |
| * | | 1:00PM | Madonna | @ | Concordia | 68-79 | |
| | Concordia ties school record for conference wins in a season |
| * | | 1:00PM | Aquinas | @ | Siena Heights | 59-38 | |
| * | 20 | 5:30PM | Davenport | @ | Madonna | 72-62 | |
| * | | 5:30PM | UM-Dearborn | @ | Aquinas | 55-79 | |
| * | | 7:30PM | Indiana Tech | @ | Cornerstone | 34-73 | |
| * | | 7:30PM | Concordia | @ | Siena Heights | 60-47 | |
| * | 23 | 1:00PM | Indiana Tech | @ | Davenport | 29-68 | |
| | Panthers Repeat as WHAC Champions |
| * | | 1:00PM | Concordia | @ | Aquinas | 49-68 | |
| | Regular-season finale; #25 AQ has four-game win streak |
| * | | 3:00PM | Cornerstone | @ | Siena Heights | 64-56 | |
| | Rescheduled from postponed game Feb. 6 |
| | 28 | 7:30PM | Indiana Tech | @ | Davenport | 52-86 | |
| | WHAC Championships - 1st Round |
| | | 7:30PM | Concordia | @ | Madonna | 51-70 | |
| | WHAC Championships - 1st Round |
| | | 7:30PM | UM-Dearborn | @ | Cornerstone | 47-70 | |
| | WHAC Championships - 1st Round |
| | | 7:30PM | Siena Heights | @ | Aquinas | 64-81 | |
| | WHAC Championships - 1st Round |
| March |
| | 1 | 1:00PM | Aquinas | @ | Cornerstone | 62-53 | |
| | WHAC Championships - Semi-final |
| | | 1:00PM | Madonna | @ | Davenport | 67-64 | |
| | WHAC Championships - Semi-final |
| | 4 | 7:30PM | Madonna | @ | Aquinas | 79-84 | |
| | WHAC Tournament -- Championship; #22 AQ wins tournament/qual. for DII tourn. |
| | 12 | 9:30AM | Davenport | vs. | Southwestern College | 76-66 | |
| | 2008 NAIA DII National Championship - First Round Game |
| | 13 | 1:00PM | Aquinas | vs. | Benedictine College | 57-79 | |
| | 2008 NAIA DII National Championship - First Round Game |
| | | 5:00PM | Cornerstone | vs. | Sterling College | 64-55 | |
| | 2008 NAIA DII National Championship - First Round Game |
| | 14 | 9:30AM | Davenport | vs. | Concordia University | 72-82 | |
| | 2008 NAIA DII National Championship - Sweet 16 |
| | | 8:00PM | Cornerstone | vs. | Northwestern College | 57-86 | |
| | 2008 NAIA DII National Championshp-Second Round Game |
